In Canada, Health Canada serves as the central regulatory authority tasked with safeguarding public health through comprehensive oversight of pharmaceuticals. Canada's regulatory framework is anchored by the Drug Identification Number (DIN) system, which forms the backbone of the country's commitment to pharmaceutical traceability, safety, and quality assurance throughout the supply chain.

In Brazil, the pharmaceutical landscape is underpinned by a commitment to ensuring the safety and authenticity of medicinal products. The Brazil National Agency of Sanitary Surveillance (ANVISA) has implemented stringent traceability requirements aimed at fortifying the pharmaceutical supply chain. These regulations are designed to combat counterfeit drugs, enhance patient safety, and provide regulatory authorities with improved visibility into the movement of pharmaceuticals throughout the distribution network.

In Argentina, the National Administration of Food and Medical Technology (ANMAT) plays a pivotal role in safeguarding public health through robust regulatory measures. ANMAT's pharmaceutical traceability requirements stand as a cornerstone in the country's commitment to ensuring the authenticity and safety of medicinal products within the pharmaceutical supply chain.

In Colombia, the National Food and Drug Surveillance Institute (INVIMA - Instituto Nacional de Vigilancia de Medicamentos y Alimentos) serves as the cornerstone regulatory authority safeguarding public health through comprehensive pharmaceutical oversight. Colombia's track and trace regulations represent the nation's commitment to pharmaceutical security, ensuring product authenticity and patient safety throughout the entire supply chain from manufacturing to patient administration.